Polyp Synchronous

In the S. cerevisiae synchronous culture, an increased P uptake from the culture medium during DNA synthesis was observed (Gillies et al., 1981). At a high level of external Pi, this uptake provided the necessary phosphorus level in cells and the 31P NMR-visible PolyP remained constant. However, if the external Pi content was low, this PolyP was consumed, acting as a substitute for the phosphate reserve (Gillies et al., 1981). 

Figure 8.14 Changes in the content of nucleic acids, phospholipids, Pi and PolyPs, and the activities of exopolyphosphatase (PolyPase) and pyrophosphatase (PPase) during synchronous growth of Schizosaccharomyces pombe (Kulaev et al., 1973b) (a) 1, number of cells PL, phospholipids OP, P J P, total phosphate (b) PPi, acid-soluble polyphosphate PP2, salt-soluble polyphosphate (c) PP3, alkali-soluble polyphosphate PP4, hot-perchloric-acid-soluble polyphosphate JZPolyP, total polyphosphate.

The incidence of synchronous neoplasia in the colon has been described at a rate of 1.5-9%. Adenomas harboring in the colon in patients with colon cancer have been reported at an incidence of 27-55%. Fenlon et al. compared CTC to pre-operative double contrast barium enema in the evaluation of patients with an obstructing carcinoma (Fenlon et al. 1999a). CTC identified all ofthe cancers including 2 synchronous cancers proximal to the obstructing mass that were missed by barium enema (Fenlon et al. 1999a). In addition, CTC demonstrated 16 of 18 polyps in the proximal colon. 

Nain D, Haker S, Eric W et al. (2002) Intra-patient prone to supine colon registration for synchronized virtual colonoscopy. In Dohi T, Kikins R (eds) Lecture notes in computer science. Springer, Berlin Heidelberg New York, pp 573-580 Nappi J, Yoshida H (2002) Automated detection of polyps with CT colonography evaluation of volumetric features for reduction of false-positive findings. Acad Radiol 9 386-397... 

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