Polyol glycosyl acceptors

The synthesis of branched saccharides by multiple glycosylations onto a central monosaccharide normally requires the use of orthogonal protecting groups in the acceptor. In this context, regioselective glycosylation of diols or polyols would ease the number of protection-deprotec-tion steps in these synthetic protocols. 

Occasionally, it is possible to glycosylate one secondary alcohol over another, and the most common examples include preferential glycosylation of equatorial hydroxyl groups over their axial counterparts.119 187,192 196 Among many applications, acceptor polyols are commonly used for the introduction of bulky... 

Glycosylation of acceptor polyols has also been used for the concomitant introduction of multiple copies of the same residue,81,85 86 89 and for generating combinatorial libraries of oligosaccharides.199-202 In a number of cases, the regioselectivity could be... 

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