Polymer-supported reagents, general application

Macroporous resins are generally highly (>5%, typically 20-25%) crosslinked polystyrene microbeads [9,10,21]. The term macroporous refers to their inner skeleton, which is made of a permanent porous structure even in the dry state (cf Scheme Ic). Historically, functionalised macroporous resins have mainly been used for ion exchange and separation. Nowadays, many new applications, especially in the field of polymer-supported reagents [31, 32] and catalysts [5,7], have been developed. 

In summary, development of functional polymers that can act as efficient organocatalysts is at the origin of the application of modified polymers as reagents and catalysts in chemistry. To date, the most successful accomplishments have been carried out in the area of basic and acid catalysts. Not surprisingly, this area includes some of the most important industrial applications for supported reagents and catalysts. In general, the development of non-chiral polymer-supported organocatalysts is a field of research that involves both industrial and academic research. In many cases, it has been possible to demonstrate how the use of the... 

There have been a range of books published on polymer-supported chemistry,including many focused purely on supported catalysts and their applications. For supported complexes reported before 1981, the reader is directed to the chapter by Pittman in COMC (1982) as well as that by Bailey and Langer. There are numerous reviews on the general area of supported catalysis and reagent chemistry including a major review by Ley and co-workers and a series of review articles published in 2002 on recoverable catalysts and reagents. However, the majority of these have been focused particularly on the use of supported complexes rather than their preparation. Supported catalysts have also been used for rapid production of compound libraries. Also, there has been an... 

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