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Polymer-Drug Conjugation Strategy and Possible Benefits

The variety of platinum-containing compoimds that exhibit reasonable inhibition of cancer cell lines is large as indicated by the preceding discussion. The structures for potentially useful platinum-containing polymers should also be variable. [Pg.133]

POLYMER-DRUG CONJUGATION STRATEGY AND POSSIBLE BENEEITS [Pg.133]

One approach to circmnvent these deficiencies is to convert the active agent into some form of prodrug that will encounter minimal interference by scavenger mechanisms. This prodrug will be able to cross intercellular membranes and approach the target site, which in cancer chemotherapy means being able to breach the lysosomal compartment of the cancerous cell. [Pg.134]

VII. POLYMER-DRUG CONJUGATION STRATEGY AND POSSIBLE BENEFITS... [Pg.119]

Polymer-Drug Conjugation Strategy and Possible Benefits 133... [Pg.133]



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Conjugation Strategies

Drug benefits

Drug conjugates

Drug conjugation

Drug strategy

Drug, drugs strategies

Polymer drugs

Polymer-drug conjugate

Polymers conjugation strategy

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