Polymer continued bioactive

Processes based on fluidized bed coating have been developed (49). In this process, the bioactive agent is dissolved in an organic solvent along with the polymer. This solution is then processed through a Wurster air suspension coater apparatus to form the final microcapsule product. A solvent partition technique based on continuous injection of a polymer-drug solution into flowing mineral oil has been reported (50). 

Water soluble polymers are well represented in the human environn nt and in food. Thus, our very existence constitutes solid proof of the lack of the physiological effects of many of these compounds. Nevertheless, some water soluble synthetic polymers, even at very low concentrations, influence enzymatic processes that form the basis of the physiology of the body. The reason for a general lack of bioactivity of synthetic polymers on the organism s level is the inability of polymers to penetrate to the location where the body s basic biochemical processes occur. The human body s most prevailing component is water (>fi)%). However, this body of water is not a continuous phase, it is subdivided by lipid membranes into spaces of microscopic size. Lipids constitute about 15% of body weight and a considerable portion of that amount is used to form and maintain cellular membranes, a structural element of the body that diminishes the mobility of hydrophilic polymers in organisms. 

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