Polymer chip, fabrication imprinting

Kitamura et al. examined the photodegradation of phenol by a silica-supported porphyrin derivative in polymer microchannel chips [15]. With an imprinting method, they fabricate dam-structured microchannel chips. The channels are filled with silica gel particles, which are modified with monopyridyltriphenylporphyrin (PyTPP). The Si-PyTPP particles act as photosensitizers (Scheme 16.9). 

Similarly, many reactors with integrated mixers and other functionality can be manufactured on one substrate to form, e.g., a combinatorial synthesis platform. Such microfluidic platforms may approach the complexity of VLSI electronic circuits, see e.g. [64], which gives an example fabricated by soft lithography (imprinting) in the polymer PDMS or [65], which gives an example in laser-machined laminated Mylar sheets. The combinatorial aspect of these examples consists in mixing chemicals in different ratios to achieve concentration series in a discrete way (i.e. a different concentration for each microchannel) which are subsequently used in a chemical reaction on the same microfluidic chip. 

O.Y.F. Henry, S.A. Piletsky and D.G. GuUen, Fabrication of molecularly imprinted polymer microarray on a chip by mid-infrared laser pulse initiated polymerisation, Biosens. Bioelectron., 23 (12) 1769-1775, 2008. 

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