Polyethylene pins

Geysen et al. [1] introduced this method for generating peptides in a reusable form. In this method, peptides are synthesized on polyaciylate-grafted polyethylene pins arranged in standard 96-well microtiter plate format, and screening is performed by an enzyme-... 

As mentioned earlier, the first peptide library with a limited number of peptides was generated by using multipin technology in 1984 (1). In this method, acrylic acid is irradiation-grafted onto the tip of polyethylene pins. Each pin is inserted into... 

A number of novel approaches to parallel synthesis have been reported. For example, synthesis of peptides on grafted polyethylene pins spatially arrayed in 96-well microtiter plate format has been described (64). In this way, a carrier containing 96 grafted pins is inserted into a 96-well microtiter plate to expose the polymer-bound substrate to soluble reagents. The reagents are removed by simply lifting the pin carrier from the reagent solutions in the microtiter plate. Application of this method to synthesis of nonpeptides has also been reported (65). 

Carrier Methacrylie acid/dimclhylacrylamide grafted polyethylene pins... 

Wiesmiiller KH, Treffer U, Spohn R, Jung G (1993) Fully automated synthesis of peptides on polyethylene pins. In Eberle AN, Schneider CH (eds) Peptides 1992 308-309. Escom, NL-Leiden. 

A mobile polymeric surface suitable for peptide synthesis can be radiation grafted to more rigid plastic (polypropylene or polyethylene) pins or small... 

Figure 15 Handles attached to derivatized polyethylene pins.

When sliding occurred between high density polyethylene pin and glass surfaces, there was no transfer of polymer on the smooth surface but there was some transfer on the abraded surface. The large fluctuations in the coefficient of friction in sliding against the smooth surface (Figure 4) indicate intermittent fracture of adhesive junctions at the interface. It was accompanied by a wear rate of... 

Figure 3. High density polyethylene pin worn against a ground steel disc.

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