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Polyelectrolyte complexes shaping

Keywords Co-assembly Cylindrical polyelectrolyte brushes Interpolyelectrolyte complexes Ionic amphiphilic block copolymers Micelles Polyelectrolytes Star-shaped polyelectrolytes... [Pg.131]

The unique stmcture of cylindrical bmshes makes them ideal candidates to (1) experimentally and theoretically study the phase separation in quasi -ID molecular objects, (2) investigate the properties of polyelectrolyte complexes of shape-persistent polyions, (3) elucidate the adsorption on planar surfaces, and eventually (4) develop novel cationic carriers for gene transfection, as described in detail in Sect. 4. [Pg.165]

Muller M (2012) Sizing, shaping and pharmaceutical applications of polyelectrolyte complex nanoparticles. Adv Polym Sci. doi 10.1007/12 2012 170... [Pg.62]

Mende M, Schwarz S, Zschoche S, Petzold G, Janke A (2011) Influence of the hydro-phobicity of polyelectrolytes on polyelectrolyte complex formation and complex particle structure and shape. Polymers 3 1363... [Pg.63]

Sizing, Shaping and Pharmaceutical Applications of Polyelectrolyte Complex Nanoparticles... [Pg.197]

Sizing, Shaping and Phannacentical Applicatiims of Polyelectrolyte Complex... [Pg.211]

Nanosized and stable chitosan-g-PEG/heparin polyelectrolyte complexes were developed by Bae et al. [133]. The nanocomplex was utilized to study apoptotic death of cancer cells. The prepared polyelectrolyte complex micelles had a spherical shape with an average diameter of 162.8 18.9 nm. They were highly stable and well dispersed even in the presence of serum due to the presence of a hydrophilic PEG shell layer surrounding the micelles. The polyelectrolyte complex micelles were internalized by cancer cells to a greater extent than free heparin alone, indicating that the dramatic cell death was attributed to the increased cellular uptake of heparin. The internalized heparin was shown to induce apoptotic death of the cancer cells via a caspase-dependent pathway. The proposed chitosan-g-PEG/ heparin polyelectrolyte complex micelles facilitated the intracellular delivery of heparin, triggered the caspase activation, and consequently promoted apoptotic death of cancer cells [133]. [Pg.80]

See other pages where Polyelectrolyte complexes shaping is mentioned: [Pg.96]    [Pg.67]    [Pg.114]    [Pg.171]    [Pg.270]    [Pg.95]    [Pg.444]    [Pg.40]    [Pg.86]    [Pg.97]    [Pg.101]    [Pg.148]    [Pg.234]    [Pg.694]    [Pg.64]   
See also in sourсe #XX -- [ Pg.222 ]



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