Polydimethylsiloxane soft lithography

The top microfluidic architecture was fabricated using a multilayer soft lithography technique with polydimethylsiloxane (PDMS). In the figure, we illustrate a... 

Keywords wrinkling Thin-film Elastomeric polymer Polydimethylsiloxane Patterns Deformation Surfaces Self-assembly Polyelectrolyte multilayer films Thin-films Polymer brushes Colloidal crystallization Mechanical-properties Assembled monolayers Buckling instability Elastomeric polymer Tobacco-mosaic-virus Soft lithography Arrays... 

FIGURE 20.10 Soft lithography replication method using polydimethylsiloxane process flow. 

To characterize the devices and use them for applications like cancer stem cell sorting and blood cell sorting, standard soft lithography was used to fabricate devices in PDMS. An SU-8 photoresist master was used to cast PDMS (polydimethylsiloxane). The patterned PDMS was sealed with T73 glass slide using corona discharge. The patterned PDMS was sealed with... 

PDMS Polydimethylsiloxane, popular structural material for the fabrication of microfluidic devices based on soft lithography RTD Residence time distribution... 

The use of polymeric materials in microchips has gained popularity, especially in the fabrication of low-cost, disposable devices [3], It is particularly common to prototype polydimethylsiloxane (PDMS) chips, which can easily be fabricated using the soft lithography technique. This fabrication strategy is considered as a low-expertise route of microscale prototyping. It facilitates creation of micropatterns on a surface or within a microfluidic channel without the need for using photochemical processes [9]. Fabrication... 

A final approach to integrating microdialysis membranes with microfluidics is based on direct bonding of microdialysis membranes with the microchannel stmctures. One such structure was developed by Bohn and colleagues [12] and is shown in Fig. 4c. Here microchannels are defined in polydimethylsiloxane (PDMS) in the soft lithography pro-... 

Soft lithography using polydimethylsiloxane is a very attractive method of rapid prototyping. ... 

Figure 9.30 A schematic diagram of the basic steps in soft lithography. (1) A mask master is produced by standard lithography methods (see, for example Figure 9.28). (2) An elastomeric material such as polydimethylsiloxane is poured over the master and, with proper processing, covers the master conformally. The resulting stamp is peeled away from the master. The material to be printed, for example an ink, is picked up with the stamp (3) and transferred to the target surface (4). The ink should be designed to adhere well to the target and only weakly to the stamp so that the stamp comes away clean from the surface (5) leaving a complete and defect-free pattern. The stamp can be re-inked and used repeatedly.

---