Polycondensation reactions immobilized enzymes

Important progress has been made on the use of immobilized enzyme catalyzed polycondensation reactions to prepare a wide range of polyesters (2,83). In this book, Hunsen et al (20) describe how an inunobilized catalyst from Humilica insolens has excellent activity for polycondensation reactions between diols and diacids. The natural role of cutinases is hydrolysis of the outer cutin polyester layer on plant leaves. Cutin is made of long chain... 

A series of close-to-spherical styrene/DVB resins of varying particle size and pore diameter were employed as supports for non-covalent adsorptive attachment of CALB by hydrophobic interaction. The effect of matrix particle and pore size on CALB i) adsorption isotherms, ii) fraction of active sites, iii) distribution within supports, and iv) catalytic activity for s-CL ring-opening polymerizations and adipic acid/l,8-octanediol polycondensations is reported. Important differences in the above for CALB immobilized on methyl methacrylate and styrene/DVB resins were found. The lessons learned herein provide a basis to others that seek to design optimal immobilized enzyme catalysts for low molar mass and polymerization reactions. 

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