Poly oligo ethylene glycol

The triblock terpolymer polypropylene oxide)-h-poly[2-(dimethylami-no)ethyl methacrylate]-b-poly[oligo(ethylene glycol) methacrylate], PPO-fc-PDMAEMA-fc-POEGMA, was prepared using the PPO macroinitiator followed by the addition of CuCl, HMTETA, and DMAEMA for the polymerization of the second block and finally OEGMA for the synthesis of the final product (Scheme 54) [128]. 

POEGMA=poly[oligo(ethylene glycol methyl ether) methacrylate] PS = polystyrene... 

Fig. 7 Chemical structures of poly(oligo(ethylene glycol) [poly(OEGMA)] methacrylate) (A) 5-arm star-shaped poly(OEGMA) (B) and polyglycerol dendrimers with generation 3 (C) 4 (D) and 5 (E). (Modified from Ref l)...

Also aiming at biomedical applications are nanoscaled hydrogels, prepared in inverse miniemulsion. In crosslinked poly(oligo(ethylene glycol) monomethyl ether methacrylate) (POEOMA) nanogels hydrophilic dyes as the polymeric dye (rhodamine isothiocyanate (RITC) dextran) [41], rhodamine in combination with the drug doxorubicin [42] or gold nanoparticles with bovine serum albumin [43] could be encapsulated. 

Poly[oligo(ethylene glycol) diglycidyl ether-co-piperazine-co-oligo(propylene glycol) diglycidyl ether)] water 2009REN... 

Poly[oligo(ethylene glycol) methacrylate-6-IH, lH,2H,2H-perfluorooctyl methacrylate] carbon dioixde 2004HWA... 

Poly[oligo(ethylene glycol) metltylaciylate-co-oligo- (propylene glycol) methacrylate] ... 

Oh, J.K. Min, K. Matyjaszewski, K. Preparation of poly(oligo(ethylene glycol) monomethyl ether methacrylate) by homogeneous aqueous AGET ATRP. Macromolecules 2006, 39 (9), 3161—3167. 

Investigations were also made into surface nanostructures and their reconstruction behavior, by altering the outer environment using a series of block copolymers, namely PS-f)-poly(2-(perfluorooctyl)ethyl methacrylate) [96], PS-b-P(HEMA) [106, 107], and PS-f)-poly[(oligo(ethylene glycol) alkyl ether methacrylate), synthesized by anionic block copolymerization [116-120]. 

Figure 15 Illustration of unique features of stable biodegradable nanogels of well-controlled water-soluble polymers in the presence of a disulfide-functionalized dimethacrylate for effective targeted drug delivery. POEOMA, (poly(oligo(ethylene glycol) monomethyl ether methacrylate). Reprinted with permission from Oh, J. K. Drumright, R. Siegwart, D. J. Matyjaszewski, K. Prog. Polym. Sci. 2008, 33,448-477. Copyright 2009 Elsevier.

Another type of terpolymer but with a diblock architecture, A-b- B-co-C), is possible by GTP due to the similar reactivity of the methacrylic monomers. Tailor-made poly(2-(diethyla-mino) ethyl methacrylate)-b-poly[(oligo (ethylene glycol)... 

Klok and co-workers demonstrated recently the feasibility of a strrface-initiated ATRP to prepare polymer surface bmshes of pHEMA or poly(oligo(ethylene glycol) methacrylate) (pEGMA). These bmshes could be statistically functionalized with short peptide ligands, which have been shown to promote adhesion of human umbilical vein endothelial cells (HUVECs). ... 

Sdierman and co-workers recently utilized CB[8] ternary complexation for the conjugation of small molecules to a polymeric backbone in water. The authors used RAFT polymerization to copolymerize a 2-naphthol-functional acrylate monomer with poly[oligo(ethylene glycol)]acrylate to form a water-soluble, 2-naphthol pendant acrylate copolymer. By using UV-Vis spectroscopy and multidimensional NMR techniques, the authors could determine that several methyl viologen (MV)-functional units could be noncovalently... 

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