Biofouling properties

In contrast, other classes of polymers are not inert. They may interact strongly with the environment and adopt special functions. Examples include specific interactions with molecules and ions exploited in separation and purification techniques electrical and optical properties used in polymer solar cells, organic light emitters, and optical elements as well as properties relevant for bio-applications, such as anti-biofouling properties and specific binding of proteins. 

Since the first rigid and soft CLs (SCLs) based on methyl methacrylate (MMA) and 2-hydroxy-ethyl methacrylate (HEMA) that appeared in 1936 and 1954, respectively, - a plethora of monomers has been synthesized for preparing CLs searching for adequate optical and mechanical features, low density, enough oxygen permeability, and more recently anti-biofouling properties. - ... 

The most widely used hydrophilic sheddable group used to improve blood stability is PEG. However, sugars also have biofouling properties, and promising doxorubicin-loaded nanoparticles with reduction-induced detachment of the lactobionic acid shell have been recently reported [98]. Doxorubicin was loaded in poly(e-caprolactone)-graft-SS-lactobionic add (PCL-g-SS-LBA) nanoparticles capable of doxorubidn release after GSH treatment. 

Suzuki, H., Murou, M., Kitano, H., Ohnob, K., and Saruwatari, Y. 2010. Silica particles coated with zwitterionic polymer brush Formation of colloidal crystals and anti-biofouling properties in aqueous medium. 

Krishnan S, Ayothi R, Hexemer A, Finlay JA, Sohn KE, Perry R, Ober CK, Kramer EJ, Callow ME, Callow JA, Fischer DA. (2006) Anti-biofouling properties of comblike block copolymers with amphiphilic side chains. Langmuirll 5075—5086. 

This proposal describes the development of a new, systematic approach for qualitatively and quantitatively studying surface-biomolecule interactions by matrix-assisted laser desorption ionization (MALDl) mass spectrometry (MS). This methodology is being developed because of the profound importance that surface-biomolecule interactions play in applications where biomaterials come into contact with complex biological fluids, it can readily be shown that undesired reactions occurring in response to surface-biomolecule contact (protein adsorption, biofouling, immune response activation, etc.) lead to enormous economic and human costs. Thus, the development of analytical methodologies that allow for efficient assessment of the properties of new biomaterials and/or the study of detailed fundamental processes initiated upon surface-biomolecule contact are of critical value ... 

System s polymer film properties and free oscillation as a fluidized array resists biofouling and iron clogging... 

Berg IC, Rutland MW, Amebrant T Lubricating properties of the salivary pellicle - an AFM study. Biofouling 2003 19 365-369. 

Polymer surface modifications are omnipresent in applications where the surface properties of materials with favorable bulk properties are insufficient. By altering the surface characteristics using physical or chemical modification the desired surface properties may be achieved. Such treatments are required e.g. to enhance printability of films, the adhesion of paints, metal or other coatings, biocompatibility, protein resistances/reduced biofouling, etc. The diverse approaches met in practice include, among others, wet chemical and gas phase chemistry, plasma or corona, UV/ozone and flame treatments. In most cases surface chemical modification reactions take place that alter the surface energy in a desired way. For example,... 

Knoell T., Safank J., Cormack T., Riley R., Lin S.W., Ridgway H. (1999), Biofouling potentials of microporous polysulfone membranes containing a sulfonated polyether-ethersulfone/polyethersulfone block copolymer correlation of membrane surface properties with bacterial attachment, J Membrane Science, 157, 117-138. 

Microdiaiysis still has great potential to impact many research areas. The designs of probes and the choice of dialysis membrane are crucial. Future research effort must be used to characterize the mass transfer characteristics of different membrane materials and their fouling properties, especially in the context of biofouling when dialyzing biological solutions such as blood. Part of the success of microdiaiysis is due to the... 

Pasmore, M., Todd, R, Smith, S., et al. 2001. Effect of ultrafiltration membranes surface properties on Pseudomonas aeruginosa biofihn initiation for the purpose of reducing biofouling. 194 15-32. 

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