Poly-cistronic mRNA

As discussed In Chapter 4, many bacterial mRNAs are poly-cistronic that Is, a single mRNA molecule (e.g., the mRNA encoded by the trp operon) Includes the coding region for several proteins that function together In a biological process. In contrast, most eukaryotic mRNAs are monocistronic that Is, each mRNA molecule encodes a single protein. This difference between polycistronic and monocistronic mRNAs correlates with a fundamental difference In their translation. 

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