Poly , analysis challenge

Analysis of Nonpolar Polymers MALDl analysis of hydrocarbon polymers is a challenging task since they are chemically inert due to the absence of functional groups in their chains, making their characterization somewhat difficult. In that sense, PS is one of the most common synthetic polymers analyzed by MALDI-MS due to the presence of the phenyl functionality in PS that facilitates its easier ionization compared to other nonpolar nonfunctional polymers such as poly(butadiene), poly(isoprene), polyethylene, or poly(propylene). 

At about the same time, this laboratory got involved in the characterization of other pyrene-labeled macromolecules such as pyrene-labeled lipids associating in a membrane bilayer [52] or a 2K semi-telechelic poly(ethylene oxide) (Pyj-PEO) forming polymeric micelles in water [53] for which the notion of an excited pyrene diffusing inside a blob might be more challenging to apply. While the FBM analysis... 

Elementary mode analysis is one such computational tool that aids in the selection of genes and pathways for deletion in order to improve the production of the target metabolite. While it was first demonstrated in S. cerevisiae for the improvement of poly-/)-hydroxybutyrate production [74], one of the most highly cited applications deals with the improvement of mixed-sugar utilization by E. coli for ethanol production [55]. The challenge of mixed-sugar utilization and the solution implemented by Trinh et al. are described below. 

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