Pluripotential cell

Evans MJ, Kaufman MH (1981) Establishment in culture of pluripotential cells from mouse embryos. Nature 292 154—156... 

Significant eftort is now focusing on tissue-engineered vessels and heart valves. The history of this effort is found in the seeding or culturing of endothelium on synthetic vascular prostheses. The clinical outcomes did not justify continued development. However, rrew technology allows vascular tissue to be formed on scaffolds of either synthetic or resorbable materials. The awareness that endothelium alone was not suitable has led to the evolution of techniques to recreate the vascular tissue utilizing multiple cells types. - This approach utilizes the cell types expected in final structure, e.g., endothelium, smooth muscle cells, and fibroblasts, or pluripotential cells such as stem cells. 

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