Platinum interaction with carbon nanotubes

Due to their high chemical reactivity, certain NMs can directly interact with the assay components and catalyze reactions, giving false-positive or false-negative results. For example, some NMs (e.g., single-wall carbon nanotubes, carbon black) have been shown to reduce the tetrazolium compounds in the MTT andXTT cytotoxicity assays into the colored formazan without any cells present [61, 62], Moreover, certain NPs, like gold or platinum, were found to oxidize directly NADH, the reaction substrate LDH cytotoxicity assay. 

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