Plastics Silastic

Many plastic materials are acid resistant, among them is "Teflon (polytetrafluoroethylene). This material resists acids but does not withstand high temps. "Silastic resists nitric acid well. Polyethylene plastic and chlorinated polyethylene are also good acid resistors... 

Chlormethiazole Edisylate Chlormethiazole edisylate may penetrate or be adsorbed onto plastics and may soften plastic sets of intravenous infusions. Adverse reactions such as thrombophlebitis, fever, and headache were reported in children receiving infusions of this drug, presumably due to reaction of components of infusions sets. For intravenous infusions, the use of Teflon intravenous cannulas or motor-driven glass syringes may be preferred over plastic or glass sets containing silastic cannulae.153154... 

Electrodes are fixed to burr holes using a plastic ring and silastic ring caps (Medtronic). The position of the contacts along the trajectory of the electrode is plotted on the sagittal and frontal sections of the Schaltenbrand and Bailey atlas [1959] according to the standardization technique described elsewhere [Velasco et al, 1975]. 

Silicone polymers may be filled or unfilled, depending on the properties desired and the application. They can be cured by several mechanisms, either at room temperature by room-temperature vulcanization (RTV) or at elevated temperatures. Their final form may be fluid, gel, elastomer, or rigid plastic. There are three primary types of silicone resins (1) flexible two-part, (2) flexible one-part, and (3) rigid silicones. Silicone rubber resins for casting, potting, and other liquid processes are available from Dow Coming (Silastic) and GE Silicones. 

Liotta (12) constructed his artificial heart from a combination of different materials - Lucite, teflon, polyester urethane, and silk. It is difficult to evaluate the thrombogenic potential of this combination of materials because the longest survival was 13 hours in dogs. The principle cause of death in these animals was low cardiac output secondary to inadequate venous return. The following year in a different series of experiments Liotta (13) tried a different combination of materials. Here, although the experiments were acute in scope, thrombus formation at the blood-plastic interface was a major problem. The left ventricular assist device (LVAD) was a tube-type with the housing and valves constructed of Estane. The internal elastic tube was made of either natural rubber. Silastic, or natural rubber covered externally with Silastic. 

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