Plant biotechnology culture conditions

Downstream processing steps are also important process components and have received only limited attention. In general, however, the types of downstream processes needed to extract chemicals from cell culture would be similar to the steps involved in their extraction from whole plants. But the extraction, separation and purification steps can generally use harsher conditions than those usually employed in the biotechnology industry for the recovery of protein products from recombinant microorganisms or animal cell culture. A major emphasis is needed, however, in the integration of these steps into an overall process system. 

Bauer, S. A. W., Schneider, S., Behr, J., Kulozik, U., Foerst, P. (2012). Combined influence of fermentation and drying conditions on survival and metabolic activity of starter and probiotic cultures after low-temperature vacuum drying. Biotechnology for Enhancing Plant Production and Food Quality, 759(4), 351-357. 

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