Pinus parviflora

Reports on the anti-influenza virus activity of natural PS are recorded in the literature. From a pine cone extract of Pinus parviflora Sieb. et Zucc., an acidic polysaccharide was isolated [115,116], This compound showed significant inhibition of both the viral protein synthesis in infected cells and virion-associated RNA-dependent RNA polymerase activity. In animal models in vivo, most mice inoculated intranasally or intracerebrally with lethal doses of the influenza virus A/WSN/33 died within 12 days. However, the infectivity of the virus that had been... 

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