Picrate, sodium salt

Note Sodium Picrate, Double Salts of. When an aq soln of Na picrate (3 moles) is stirred and heated with 3 moles of finely powdered Ba or Fb picrate, the resulting double salts are less sensitive to impact than the single salts (and for this reason are less dangerous to handle). The same can be said for other picrate double salts (Ref 4)... 

The relative inaccessibility of C-AIR (107) promoted Shaw and co-workers [66JCS(C)2270] to use the 5-aminoimidazole-4-carboxylate (111 R = H) as a model compound since this was readily obtained as a crystalline sodium salt, in two steps from ethyl Af-(cyano-ethoxycarbonylmethyl)for-mimidate (110) and cyclohexylamine (Scheme 12) [62JCS(C)2937]. 5-Amino-l-cyclohexylimidazole (112 R = H) was obtained as the picrate salt (22%) from the sodium salt of the acid (111 R = H) by treatment of... 

By the same procedure, crystalline picrates of 5-amino- 1-cyclohexyl-2-methylimidazole (112 R = Me) (45%) [71JCS(C)1501] and 5-amino-l-(2-pyridyl) imidazole (96 R1 = pyrid-2-yl, R2 = H) (20%) [80JCS(P1)2316] were obtained from the sodium salts of the corresponding acids. 

The following salts of laudanine have been described hydrochloride, sulfate, oxalate, tartrate, platinichloride, aurichloride, picrate (m.p. 176-177°), and the sodium salt. 

Neutral lead picrate is prepared by reaction of aqueous solutions of picric acid [5,9, 10] or mixture of picric acid and its sodium salt [5] with lead nitrate or acetate. Lead picrate is isolated as a yellow precipitate. 

Trinltrophenol, sodium salt Sodium picrate CeHjNjNaO, 3324-58-1 251.086 nd(w) 270.4 ... 

To a concentrated solution of 0-5 g of Ae sodium salt of the acid (or 0-5 g of the pure acid) add 0 5 g of o-phenylenediamine and 4 ml of 5N hydrochloric add. Reflux for 15 minutes, cool, and add 0 880 ammonia solution imtil the alkylbenziminazole separates. Filter and wash the solid with water. Dissolve it in a minimum of alcohol and add a saturated solution of picric acid (approximately 0 5 g) in hot alcohol. Boil and cool, when the alkylbenziminazole picrate should separate. 

Identification of Amines. Picric acid combines with many amines to give crystalline picrates, of general formula B,(NO )aCeHjOH, where B is a molecule of a monacidic base. These picrates have usually sharp melting- or decomposition-points, and serve to characterise the amines concerned. They may be formed either by (a) direct union of the acid and the base in a suitable solvent, or (6) by the interaction of sodium picrate and a salt of the amine in aqueous solution. 

Dissolve a small quantity of the methiodide in cold water and add it with shaking to an excess of cold saturated aqueous sodium picrate solution. A yellow dovible salt of quinaldine niethoi icrate ami sodium picrafe. 

Thus, 5-amino-2-mercapto-l-methylimidazole (96 R = Me, R2 = SH) (65%) was obtained (48JCS2028) from 5-amino-2-methylaminothiazole (113 R1 = Me) on treatment with aqueous sodium carbonate. The aminoim-idazole (96 R1 = Me, R2 = SH) was found to be unstable in air, but gave a stable hydrochloride salt and on treatment with Raney nickel was desulfurized to give 5-amino-1-methylimidazole (96 R = Me, R2 = H) (58%), which was also unstable in air and was characterized as its picrate salt. 

The reaction of aminoguanidine bicarbonate (84) with sodium nitrite in the presence of excess acetic acid produces 1,3-ditetrazolyltriazine (89), another nitrogen-rich heterocycle (C2H3N11 = 85 % N) which readily forms explosive metal salts. The reaction of aminoguanidine bicarbonate (84) with sodium nitrite in the presence of mineral acid yields guanyl azide (90), of which, the perchlorate and picrate salts are primary explosives. Guanyl azide (90) reacts with sodium hydroxide to form sodium azide, whereas reaction with weak base or acid forms 5-aminotetrazole. ... 

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