Phytoestrogens and Mycoestrogens

Branham et al. [11] used an ER-ligand binding assay to measure the RBA for 46 chemicals considered to be potential phytoestrogens and mycoestrogens. The classes of chemicals examined (flavones, isoflavones, flavanones, coumarins, chalcones, and mycoestrogens) are shown in Figure 18.8. Representative chemicals from each of these classes showed some affinity for ER, ranging widely in RBAs from 43 to 0.00008 E2 = 100). No further work was done to describe specific SARs for these classes. 

Branham WS, Dial SL, Moland CL, Hass BS, Blair RM, Fang H, Shi L, Tong W, Perkins RG, Sheehan DM. 2002. Phytoestrogens and mycoestrogens bind to the rat uterine estrogen receptor. J Nutr 132 658-664. 

In general, xenoestrogens in the environment are separated into those occurring naturally (produced by either plants or fungi) and those produced commercially (e.g., insecticides, herbicides, estrogen-like therapeutics, and industrial by-products). Phytoestrogens and mycoestrogens are found in various... 

Phytoestrogens and mycoestrogens with suspected endocrine-associated effects... 

It is generally accepted that the assessment of actual risks or benefits of phytoestrogens and mycoestrogens... 

Estrogens III Phytoestrogens and Mycoestrogens, Pages 251-254, James L. Wittliff, Sarah A. Andres and D. Alan Kerr SummaryPlus Full Text + Links PDF (80 K)... 

Many natural chemicals also have endocrine disruption effects, including chemicals in plants (phytoestrogens) and fungi (mycoestrogens). These endocrine disrupters... 

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