Physical Forms of MIPs

Based on the methods of production and with an eye on the final applications of the MIPs, which can range from selective removal or detection of target species to chromatographic and sol phase separations and drug delivery mechanisms, MIPs are produced in different physical forms and structures, ranging from films and beads to 

Monolithically structured MIPs that have been prepared through bulk polymerization procedures have been used for capillary electrophoresis [141-143] and solid-phase microextraction (SPME) [144], as well as other analytical techniques like the chiral analysis of propranolol [145] or in competitive radio-labeled MIAs [146] and liquid chromatography [ 17,20,31,69-72]. 

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The aim of this chapter is to provide the reader with a comprehensive, although not necessarily exhaustive, overview of the methods proposed up to now for the preparation of predetermined physical forms of MIPs. The subject will be organised according to the type of form as well as according to the employed preparation strategy. In the course of the last years, other less extensive reviews on this research area have been published, and the interested reader is referred to them as well [1-5]. 

Biffis, A., Dvorakova, G., Falcimaigne-cordin, A. (2012). Physical forms of MIPS. In Topics in Current Chemistry, Molecular Imprinting (Haupt, K., ed.). Springer, New York. 

A. Biffis, G. Dvorakova and A. Falcimaigne-Cordin, Physical forms of MIPs, in Molecular Imprinting, K. Haupt (Ed.) Springer Berlin/Heidelberg, Topics in Current Chem. series, 325 29-82, 2012. 

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