Phylogenetic analysis, structural motifs

Figure 1. Molecular architecture and phylogenetic analysis of coronin 7 proteins. A), Domain structure of human coronin 7. Core domains consisting of WD repeats are preceded by "coronin signature" motifs. Note the low complexity proline, serine- and threonine-enriched domain preceding the second core. B), Partial comparison of amino acid sequences of human coronin 7 (top), Drosophila PODl isoform A (middle) and C. elegans POD-1 (bottom). Predicted Yxx motifs are highlighted in gray and boxed. C), Partial comparison of amino acid sequences of human, dog, mouse and rat coronin 7 (top to bottom). Predicted Yxxo motifs are highlighted in gray and boxed. See text for details.

---