Phthalates Expert Panel

Kavlock R, Boekelheide K, Chapin R, Cunningham M, Faustman E, Foster P, Golub M, Henderson R, Hinberg I, Little R, Seed J, Shea K, Tabacova S, Tyl R, Williams P, Zacharewski T (2002) NTP Center for the evaluation of risks to human reproduction phthalates expert panel report on the reproductive and developmental toxicity of di-isononyl phthalate. Reprod Toxicol 16 679-708... 

JThe CERHR Phthalates Expert Panel held its third and final meeting 12-13 July 2000 in Arlington, Virginia the CERHR final reports on the seven phthalates evaluated along with a full description of the center and its activities are available on the CERHR Web site. 

Kavlock, R., K. Boekelheide, R. Chapin, M. Cunningham, E. Faustman, P. Foster, M. Golub, R. Henderson, I. Hinberg, R. Little, J. Seed, K. Shea, S. Tabacova, R. Tyl, P. Williams, and T. Zacharewski. 2002. NTP Center for the Evaluation of Risk to Human Reproduction Phthalates expert panel report on the reproductive and development toxicity of di(2-ehtylhexyl) phthalate. Reprod. Toxicol. 16(5) 529-653. 

NTP. 2000b. NTP-CERHR expert panel report on cli (2-et/wlhexyl)phthalate. NTP-CERHR-DEHP-00. U.S. Department of Health and Human Services, National Toxicology Program, Center for the Evaluation of Risks to Human Reproduction available at http //cerhr.niehs.nih.gov/news/index.html. May 11, 2000. 

Few exposure data were available for DIDP, DnOP, DINP, and DrrHP, the latter of which is used in PVC intended for food applications (i.e., bottle cap liners, seam cements). Therefore, the NTP Expert Panel did not calculate exposme estimates for these phthalates. It is anticipated that exposure to each does not exceed exposirre levels calculated for DEHP. Other phthalate exposure in adults may result from environmen-... 

In 1993, the toy industry and the U.S. Consumer Product Safety Commission (CPSC) agreed that DOP (DEHP) would be eliminated from soft teethers and rattlers. As a precautionary move, the toy industry elected to remove all phthalates from these articles. In December 1998, after being asked to ban all vinyl toys, the CPSC issued an initial report on DINP stating that few if any children are at risk. Similar conclusions were reached following a review of the safety of DINP in toys by a panel of experts chaired by former Surgeon General C. Everett Koop. In their 1999 report, the experts concluded that DINP in toys is not harmful for children in the normal use of these toys. " ... 

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