Phosphorylcholine analogs

F. S. Lee, Z.-T. Chu, M. B. Bolger, and A. Warshel, Protein Eng., 5, 215 (1992). Calculations of Antibody—Antigen Interactions Microscopic and Semimicroscopic Evaluation of the Free Energies of Binding of Phosphorylcholine Analogs to McP603. 

Lee, P.S., Chu, Z-T., Bolger, M.B., and Warshel, A. (1992) Calculations of antibody-antigen interactions microscopic and semi-microscopic evaluation of the free energies of binding of phosphorylcholine analogs to McPC603, Prot. Eng. 5, 215-228. 

Lee et al. used Warshel s program ENZYMIX to run FEP calculations on the relative binding free energies of phosphorylcholine analogs to the murine myeloma protein McPC603. Initial coordinates were taken from a corresponding X-ray structure.265 The and AAG Pj values for the 3-carbox-... 

The addition of phosphorylcholine to ceramide produces sphingomyelin (Fig. 36.2). Sphingomyehn (also known as ceramide phosphorylcholine) is analogous to phosphatidylcholine. 

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