Phosphorylation phosphoryla tion

The biological transformations that involve ATP are both numerous and funda mental They include for example many phosphorylation reactions m which ATP trans fers one of its phosphate units to the —OH of another molecule These phosphoryla tions are catalyzed by enzymes called kinases An example is the first step m the metabolism of glucose... 

Glycogen content phosphoryla tion Low phosphorylation glycolysis Intermediate High... 

The reactivities of some new phosphorylating agents based on 2-oxo-l,3-oxazolidine have been discussed in terms of electron delocalizations. The chemistry of phosphorylated benzimidazolides has been discussed (67 refs.). Noteworthy is the displacement of a nitro group, with resultant C-phosphoryla-tion, when 5(6)-nitrobenzimidazole is treated with secondary phosphite anions. ... 

Nord (64) observed that the induction period is greatly decreased by adequate stirring of their 3-10% yeast suspension. There are also effects of stirring considered by Weichherz and Nord (92) in the latter part of the fermentation, i.e., a phase corresponding to the slow fermentation phase noted by Meyerhof. They conclude substantially that a phosphorylation-free breakdown of substrate molecules must be considered to occur parallel to the dissimilation of phosphorylated substrates in living yeast cells. While there seems to be little tendency now to consider that phosphoryla-tion-free breakdown may occur in yeast, yet it seems quite posable that several different reaction chains occur, and two or three pathways have been shown to occur in systems derived from yeast. This situation may well refer to these different mechanisms of desmolysis. 

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