Phosphorus oxyhalides

Phosphorus-oxygen bonds, 79 26-27 Phosphorus oxyhalide, physical properties of, 79 39t... 

Sodium acetate appears to decompose a product of the condensation of methylaniline with phosphorus oxyhalides substances other than the aldehyde are largely retained in the sodium acetate solution. 

What is the most commonly used phosphorus oxyhalide, general formula POX3 What are its industrial uses How does it react with water, and how is this reaction related to the fact that it is a strong irritant to the eyes, skin, and mucous membranes ... 

Bromo and -iodoindoles can be prepared very efficiently via a-lithiation (section 17.6.1) 2-haloindoles are also available from the reaction of oxindoles with phosphorus oxyhalides. ... 

All tetrahedral halophosphates (phosphorohalidates) can in principle be prepared by reacting a phosphorus oxyhalide with the appropriate amount of alcohol or phenol (5.331, 5.332). With phos-phoryl chloride, the reaction proceeds smoothly at room temperature when R is a primary aliphatic alcohol, provided the hydrogen chloride can be removed. Usually these reactions are carried out in an inert solvent at or below room temperature with a suitable base added to remove the HCl. 

Other phosphorus oxyhalides form as a result of the reactions of POCI3 with metal fluorides or iodides. 

The phosphorus halides and oxyhalides are important compounds in organic chemistry and serve as starting materials for the production of many phosphorus-containing compounds. Many of the key compounds in pesticides, oil additives, fire retardants for clothing, and surfactants (agents that act at surfaces), for example, are commercially made from phosphorus oxyhalides. 

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