Phosphorous acid amides

N,N -Bis( -chloroethyl)phosphoric acid amide dichloride T riethylamine 1,3-Propanolamine... 

N,N-bis-(2amine hydrochloride Triethylamine... 

N,N -Bis(/3[Pg.1617]

I Aliphatic ethers, nethvl t-butyl ether, tetramethylguanidine, hexamethyl phosphoric acid amide (trialkyleuaines)... 

Stereoselective l.4-reduction oi the 1.3-butadiene system to olefin 57 lakes place tinder the conditions of the Birch reduction. Intramolecular protonation of the intermediate carbanion at the 18-position to give 57 occurs with high selectivity syn to the hydroxymethy-iene group Conversion into phosphoric acid derivative 58 and cleavage of the phosphoric acid amide group under (he conditions of the Bcnkeser reduction provides compound 5921 Fluonde ion causes the release of free p-amyrin (1) in a final step I Li, NH3(iyTllF (1/1.75), -78 C 93%. 

Allyl bromide Hexamethyl phosphoric acid amide... 

A solution of 7.5 g (0.1 mol) of 1,3-propanolamine and 20.2 g of triethylamine in 100 cc of absolute dioxane is added dropwise at 25°C to 30°C while stirring well to a solution of 25.9 g (0.1 mol) of N,N-bis-(p-chloroethyl)-phosphoric acid amide dichloride in 100 cc of absolute dioxane. After the reaction is complete, the product is separated from the precipitated triethylamine hydrochloride and the filtrate is concentrated by evaporation in waterjet vacuum at 35°C. The residue is dissolved in a large amount of ether and mixed to saturation with water. The N,N-bis-(p-chloroethyl)-N,O-propylene phosphoric acid diamide crystallizes out of the ethereal solution, after it has stood for some time in a refrigerator, in the form of colorless water-soluble crystals. MP 48°C to 49°C. Yield 65% to 70% of the theoretical. 

Phosphorous acid, 4 55 Phosphorous acid amide imide, formation of, from phosphoryl triamide, 6 111... 

The reaction of 5-adenylic acid 522 with aqueous ammonia in the presence of DCC affords an 87 % yield of adenosine 5-phosphoric acid amide 523." ... 

Phosphorus in mineral form is bound in phosphates (Ca, Mg, Fe, Al) or in the soil colloidal complex in the form of phosphoric acid amides. Phosphorus bound to organic substances is also of importance. 

Fig. 199. Preparation of phosphoric acid amides according to Goehrlng and Nledenzu. a) reaction tube h) condensation trap and Storage tube f) glass frit h-i-h stopcocks s) ball and socket joint.

N,N-bis((3-chloroethyl)phosphoric acid amide dichloride Ethylene chlorohydrin... 

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