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Phospholipid-modified poly

Seki and Tirrell [436] studied the pH-dependent complexation of poly(acrylic acid) derivatives with phospholipid vesicle membranes. These authors found that polyfacrylic acid), poly(methacrylic arid) and poly(ethacrylic acid) modify the properties of a phospholipid vesicle membrane. At or below a critical pH the polymers complex with the membrane, resulting in broadening of the melting transition. The value of the critical pH depends on the chemical structure and tacticity of the polymer and increases with polymer hydro-phobicity from approximately 4.6 for poly(acrylic acid) to approximately 8 for poly(ethacrylic acid). Subsequent photophysical and calorimetric experiments [437] and kinetic studies [398] support the hypothesis that these transitions are caused by pH dependent adsorption of hydrophobic polymeric carboxylic acids... [Pg.35]

Harasym, T. O., Tardi, P., Longman, S. A., Ansell, S. M., Bally, M. B Cullis, P. R. C., and Choi, L. S. L. (1995) Poly(ethylene glycol)-modified phospholipids prevent aggregation during covalent conjugation of proteins to liposomes. Bioconj. Chem. 6, 187-194. [Pg.67]

See other pages where Phospholipid-modified poly is mentioned: [Pg.214]    [Pg.127]    [Pg.127]    [Pg.214]    [Pg.127]    [Pg.127]    [Pg.197]    [Pg.324]    [Pg.228]    [Pg.207]    [Pg.271]    [Pg.201]    [Pg.166]    [Pg.156]    [Pg.170]    [Pg.352]    [Pg.3]    [Pg.1055]    [Pg.72]    [Pg.230]    [Pg.725]    [Pg.468]    [Pg.66]    [Pg.153]    [Pg.120]    [Pg.468]    [Pg.452]    [Pg.205]   
See also in sourсe #XX -- [ Pg.126 ]



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