Phosphatidylinositol-synthase

PHOSPHATIDYLINOSITOL SYNTHASE CDP-Diacylglycerol L-serine O-phosphatidyl-transferase,... 

PHOSPHATIDYLINOSITOL SYNTHASE 1-Phosphatidyl-1 D-myo-inositol 4,5-bisphos-phate synthesis,... 

PHOSPHATIDYLINOSITOL SYNTHASE Phosphatidyl-N-methylethanolamine, PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE PHOSPHATIDYL-N-METHYLETHANOL-AMINE N-METHYLTRANSFERASE... 

Nikawa, J., and Yamashita, S., 1997, Phosphatidylinositol synthase from yeast. Biochim. Biophys. Acta 1348 173-178. 

Wengelnik, K., and Vial, H. J. (2007). Characterisation of the phosphatidylinositol synthase gene of Plasmodium species. Res. Microbiol. 158,51-59. 

Elabbadi, N., Acelin, M. L. and Vial, H. J. (1994) Characterization of phosphatidylinositol synthase and evidence of a polyphosphoinositide cycle in Plasmodium-infected erythrocytes. Mol. Biochem. Parasitol. 63 179-192. 

SOLUBILIZATION AND SELECTIVITY OF THE PHOSPHATIDYLINOSITOL-SYNTHASE FROM ETIOLATED MAIZE COLEOPTILE MICROSOMES... 

Hmyene A, Guerbette F, Justin AM, Mazliak P, Kader JC. Solubilization of phosphatidylinositol-synthase from maize seedlings. In Quinn PJ, Harwood JL, editors. Plant Lipid Biochemistry, Stracture and Utilization. Londres Portland Press, 1990 263-265. 

Today s mitochondria lack most of the genes involved in phosphohpid metabolism. Therefore, mitochondria have to import most of their hpids. Phospholipids such as phosphatidylcholine, phosphatidylserine, phosphatidylglycerol, and phosphatidylinositol must be synthesized in the endoplasmatic reticulum under the control of nuclear genes and then transferred to mitochondria (Voelker, 2000) (Figure 1). Mitochondria use both nuclear and mitochondrial encoded proteins to further diversify phospholipids (Dowhan, 1997 Kent, 1995 Daum, 1985). Thus, a nuclear phosphatidylserine decarboxylase converts phosphatidylserine into phosphatidylethanolamine, or mitochondrial encoded cardiolipin synthase converts phosphatidylglycerol into cardiolipin which is incorporated exclusively into the inner mitochondrial membrane. 

Lorenz, M., Wessler, S., Follmann, E., Michaelis, W., Dusterhoft, T., Baumann, G., Stangl, K, and Stangl, V., A constituent of green tea, epigallocatechin-3-gallate, activates rndothelial nitric oxide synthase by a phosphatidylinositol-3-OH-kinase-, cAMP-dependent protein kinase-, and Akt-dependent pathway and leads to endothelial-dependent vasorelaxation, J. Biol Chem., 279, 6190, 2004. 

Wang, D. Sul, H.S. Insulin stimulation of the fatty acid synthase promoter is mediated by the phosphatidylinositol 3-kinase pathway. Involvement of protein kinase B/Akt. J. Biol. Chem., 273, 25420-25426 (1998)... 

FIGURE 15-29 The path from insulin to GSK3 and glycogen synthase. Insulin binding to its receptor activates a tyrosine protein kinase in the receptor, which phosphorylates insulin receptor substrate-1 (IRS-1). The phosphotyrosine in this protein is then bound by phos-phatidylinositol 3-kinase (PI-3K), which converts phosphatidylinositol... 

Kang KW, Choi SH, Kim SG. 2002. Peroxynitrite activates NF-E2-related factor 2/ antioxidant response element through the pathway of phosphatidylinositol 3-kinase The role of nitric oxide synthase in rat glutathione S-transferase A2 induction. Nitric Oxide 7 244-253. 

BEO, bergamot essential oil GSK-3/3, glycogen synthase kinase-3/3 MCAo, middle cerebral artery occlusion PI3-K, phosphatidylinositol 3-kinase... 

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