Phosphate in E. coli

U.9 Phospholipid biosynthesis (general).- A few only of the very many papers published in this area that appear to have particular mechanistic importance can be described here. Stable carbon isotope ratios ( C/ C) at natural abundance levels were determined for each of the major fatty acid components of the phospholipids of E. coli. The results were consistent with a model of lipid metabolism in which fatty acids were released from the fatty acid synthase in free form, and required re-activation to the acyl-acyl carrier protein prior to esterification. A close coupling of fatty acid and phospholipid synthesis was implied. The characteristics of fatty acid transfer from acyl-acyl carrier protein to sn-glyoerol- -phosphate in E. coli have been inves-... 

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