Phenylsuccinic anhydride

Phenylsuccinic anhydride Methyl amine Acetyl chloride... 

Phenylacetylene, 72 /ra X-TPHENYL-l,3-BUTAniENE, 75 a-PHENYL-a-CARBETHOXYGLUTARO-NITRILE, 80, 82 0-Phenylenediamine, 56, 86 a-Phenylglutaric acid, 82 a-PHENYLGLUTARIC ANHYDRIDE, 81 Phenylhydrazine, 90 Phenylmagnesium bromide, 97 Phenylsuccinic acid, 83 Phenylsuccinic anhydride, 85 Phosphoric acid, ortho-, 33, 34 Phosphoric anhydride, 33 Phosphorus oxychloride, Tl Phosphorus pentoxide, 22, 46 Potassium, 19, 20 directions for safe handling of, 20 Potassium lerl.-butoxide, solution of, 19... 

The checkers found the product at this stage to be of sufficient purity for conversion to phenylsuccinic anhydride. 

Irradiation of mixtures of benzene and maleic anhydride in the presence of trifluoroacetic acid has shed more light on the mechanism of the photoaddition [36], Under these circumstances, formation of the 1 2 adduct is completely suppressed and a new 1 1 adduct, phenylsuccinic anhydride, is obtained. It was concluded from these experiments that excitation of the ground-state complex between benzene and maleic anhydride leads to a zwitterionic intermediate that can be intercepted by protonation (Scheme 5). 

Scheme 5 Formation of phenylsuccinic anhydride by irradiation of benzene and maleic anhydride in the presence of trifluoroacetic acid.

Mattes and Farid [42] have argued that the formation of phenylsuccinic anhydride need not be regarded as an indication that the ortho cycloadduct is formed via a zwitterionic intermediate. They considered the possibility that charge-transfer excitation of the maleic anhydride-benzene complex leads to the anhydride radical anion and the benzene radical cation. Protonation of the radical anion followed by addition to the benzene radical cation can be considered as an alternative route to phenylsuccinic anhydride. 

CUiHu)0, 635-51-8) see Phensuximide phenylsuccinic acid bis(methylammonium) salt (C jH2 N204 157399-22-9) see Phensuximide phenylsuccinic anhydride (C1hHs05 1131-15-3) see Phensuximide phenylsulfinyl chloride... 

Phenylsuccinic ACID, 30, 83 Phenylsuccinic anhydride, 30, 85 Phenyl thiourea, 31, 22 Phosgene, 31, 62... 

The first of these alternative approaches started with commercially available indanone-3-carboxylic acid 23 (derived from phenylsuccinic anhydride via Friedel-Crafts chemistry). This indanone was a viable precursor to 6 through an aminomethyl homologation with cyanide or nitromethane (Scheme 3.10). Our intent was to obtain ester 25, which after reduction would afford methylamine 28, which in turn would cyclize to generate lactam 29, giving benzazepine 6 upon reduction. Stereocontrol in the homologation was unnecessary, as lactam 29 would theoretically provide a thermodynamic sink under epimerizing reaction conditions, capturing the desired di-indane isomer. 

Eqn. (a). Illustrates the reaction between phenylsuccinic anhydride and methyl amine in the presence of absolute dry ether to give rise to the formation of (3-N-methylphenyl-succinamic acid (I). 

Phenylpropene-l, MA copolymerization, 341 o-Phenylstyrene, MA copolymerizaiion, 373 Phenylsuccinic anhydride, 205... 

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