Phenylpropanolamine Fluoxetine

Clinically important, potentially hazardous interactions with amitriptyline, amoxapine, amphetamines, bupropion, citalopram, clomipramine, cyproheptadine, desipramine, dextroamphetamine, dextromethorphan, diethylpropion, dopamine, doxepin, entacapone, ephedrine, epinephrine, fluoxetine, fluvoxamine, imipramine, levodopa, mazindol, meperidine, methamphetamine, nefazodone, nortriptyline, paroxetine, phendimetrazine, phentermine, phenylephrine, phenylpropanolamine, pizotifen, protriptyline, pseudoephedrine, rizatriptan, sertraline, sibutramine, sumatriptan, sympathomimetics, tramadol, tricyclic antidepressants, trimipramine, tryptophan, tyramine-containing foods, venlafaxine, zolmitriptan... 

Also analyzed 6-acetylmorphine, amiloride, amphetamine, benzocaine, benzoylecgonine, caffeine, cocaine, do o lamine, fluoxetine, glutethimide, hexobarbital, hypoxanthine, le-vorphanol, LSD, meperidine, mephobarbital, methadone, methylphenidate, methyprylon, N-norcodeine, oxazepam, oxycodone, phenylpropanolamine, prilocaine, procaine, terfena-dine... 

Isolated reports describe delirium in one patient and a seizure in another when methylphenidate was taken with sertraline. Schizophrenia and symptoms of amfetamine toxicity have also been reported in two patients taking amfetamine and fluoxetine. There is an isolated report of the serotonin syndrome associated with concurrent citalopram and dexamfetamine and another associated with sertraline and etilefrine. There is also a report of adverse effects associated with fluoxetine and phenylpropanolamine. 

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