Phenyl various substituted

Phenyl-5-thiazolyl)acetic acids variously substituted in the 2-position give the corresponding naphtho[l,2]thiazoles in the presence of acetic anhydride and sodium acetate (397, 426, 857). 

Abbreviations acac, acetylacetonate Aik, alkyl AN, acetonitrile bpy, 2,2 -bipyridine Bu, butyl cod, 1,5- or 1,4-cyclooctadiene coe, cyclooctene cot, cyclooctatetraene Cp, cyclopentadienyl Cp, pentamethylcyclopenladienyl Cy, cyclohexyl dme, 1,2-dimethoxyethane dpe, bis(diphenyl-phosphino)ethane dppen, cis-l,2-bis(di[Atenylphosphino)ethylene dppm, bis(diphenylphosphino) methane dppp, l,3-bis(diphenylphosphino)propane eda,ethylenediamine Et,ethyl Hal,halide Hpz, pyrazole HPz, variously substituted pyrazoles Hpz, 3,5-dimethylpyrazole Me, methyl Mes, mesityl nbd, notboma-2,5-diene OBor, (lS)-endo-(-)-bomoxy Ph, phenyl phen, LlO-phenanthroline Pr, f opyl py, pyridine pz, pyrazolate Pz, variously substituted pyrazolates pz, 3,5-dimethylpyrazolate solv, solvent tfb, tetrafluorobenzo(5,6]bicyclo(2.2.2]octa-2,5,7-triene (tetrafluorobenzobanelene) THE, tetrahydrofuran tht, tetrahydrothicphene Tol, tolyl. 

The parent TMM precursor (1) reacts with tropones (117) to give reasonable yields of the bridged [4.3.1]decanones (118) [43]. Various substituted TMMs also cycloadd to tropone with regioselectivity similar to that of the corresponding [3+2] cases [20, 43]. Addition of MesSnOAc as a co-catalyst also leads to yield improvement [16]. In the case of a phenyl-substituted tropone and a methyl-TMM, performing the reaction under high pressure favors the formation of kinetic products (119) and (120) over the thermodynamic product (121) [11]. 

A stopped flow technique coupled with spectrophotometric analysis of the iron (II) complex formed has been used to investigate - the reactions of some organic complexes of iron(III) with the ion Fe ". The iron(III) was complexed with 1,10-phenanthroline, various substituted 1,10-phenanthrolines (5-methyl-, 5-nitro-, 5-chloro-, 5-phenyl-, 5,6-dimethyl-, 4,7-diphenyl-, and 3,4,7,8-tetramethyl-) and 2,2 -dipyridine, 4,4 -dimethyl-2,2 -dipyridine, and 2,2, 2"-tripyridine. The wavelengths used for the analysis lay in the region 500-552 m/i. 

Another important aspect is the very simple preparation of the silyltriflates. Systematic investigations of the cleavage of the silicon element bond (Si-E) by CF3SO3H have shown that the reaction rate decreases in the sequence (E=) a-naphthyl > phenyl > Cl > H > alkyl [3]. Therefore especially pure silyltriflates result from protodesilylation of arylsilanes with CF3SO3H. On the basis of these general results the synthesis of a large number of variously substituted silyltriflates [4,5] can be planned. This is of particular interest in the chemistry of oligosilanes. 

Benzofurazan oxide has also been prepared by the oxidation of o-nitroaniline with phenyl iodosoacetate.6 Other methods of preparation are given in reference 4. The hypochlorite oxidation method has been used in the synthesis of various substituted benzofurazan oxides.6... 

Various substituted phenyl and 2-naphthyl groups were introduced to the / -position of isopropyl ester 78 with enantioselectivities ranging from 93% to 97% ee in high yields in the reactions with lithium arylborates (Scheme 34).110... 

The coupling of Naphtol AS or its phenyl-substituted derivatives with diazonium salts from variously substituted anilines in aqueous alkaline solution (section 4-11) gave incomplete reactions and impure products in some instances, probably because these coupling components have inadequate solubility in aqueous media. Pure dyes in ca. 90% yields were obtained by reaction in dimethylformamide in the presence of sodium acetate. Metallisation of these o,o -dihydroxyazo ligands with sodium chromium salicylate or a cobalt(II) salt gave metal-complex dyes in 80-100% yields [22]. Specific structural isomers of these complexes were identified by i.r., n.m.r., Raman and UV/visible spectroscopy [23]. 

In the preparation and use of a series of 5 variously substituted 1-aryl-l-vinyllithium derivatives (Ar = phenyl, dimethylphenyl or isopropylphenyl Ri = H, Me or 4-tolyl R2 = D, Me or 4-tolyl), all operations had to be under purified nitrogen to prevent explosion. 

The mechanisms of aminolysis of substituted phenyl quinoline-8- and -6-carboxylates, (36) and (37), have been evaluated using AMI semiempirical and HF/6-31- -G(d) ab initio quanmm mechanical methods to study the ammonolyses of the model systems vinyl c/x-3-(methyleneamino)acrylate (38), c/x-2-hydroxyvinyl di-3-(methyleneamino)acrylate (39) and vinyl rranx-3-(methyleneamino)acrylate (40). Both experimental and computational results support the formation of a tetrahedral intermediate in the reaction. The results of this study are fully consistent with the experimental observations for the aminolyses of variously substituted phenyl quinoline-8- (36) and -6-carboxylates (37). ... 

The NH stretching band in triazole appears in the vapor phase at 3522 cm and in carbon tetrachloride at 3470 cm in the solid phase the NH absorption is a broad band at 2400-3300 cm (for 4-phenyl-triazole). The CH stretching frequency of 4- or 5-unsubstituted triazoles is at 3100-3140 cm (liquid phase).In-plane and out-of-plane deformation bands of the CH bond have also been distinguished at 1237 and 1076 cm (in the solution spectrum of 1,2,3-triazole), at 1290-1150 and 850-700 cm (for various substituted triazoles) and at 1149—1074 and 855-825 cm (for 2-aryltriazoles). ... 

Polymetalated systems of this type without phenyl substitution at the lithiated carbon centre are only accessible when solutions of LiCioHg (144a) or LiDBB (145) in THF instead of a suspension of metallic lithium in THF are reacted with bis(phenylthiomethyl)silanes of type 155. In our group, variously substituted bis(lithiomethyl)silanes 117a, 156b-e and 101 were synthesized by reductive cleavage of the carbon-sulphur bond with LiCioHg... 

Thermolysis of variously substituted meso-pentacenic photooxides leads to various isomerizations that appear to be strongly affected by the phenyl substituents. These isomerizations also go through the intermediacy of meso-diepoxides.180... 

An interesting CoMFA study was conducted by Weigt and Wiese on a set of 58 variously substituted 2-phenyl-4-quinolone and 2-phenyl-l,8-naphthyridin-4-one CSI (Chart 3) [27],... 

This reaction has been made with various carbonyl compounds, e.g., cyclopentanone,27 cyclohexanone,20 cycloheptanone,27 cycloocta-none,27 1-tetralone,21 2-tetralone,28 variously substituted acetophenones,29 phenyl benzyl ketone,29 dibenzyl ketone,29 dibenzoyl-methane,18, 30 ethyl benzoylacetate,18 ethyl malonate,30 malon-anilide,30 and 2-(bisalkylthio)methylenecyclopentanones and cyclohexanones.27... 

The significance of the coulombic field is observed (79). Figure 9 shows the catalytic activities of poly(4(5)-vinylimidazole-co-acrylic acid), poly(IM-ac), and low molecular weight imidazole derivatives in hydrolyses of various substituted phenyl acetates of which leaving groups have different activities. 

The effectiveness of various substituted BINOL ligands 12-16 in the Zr(IV)-or Ti(IV)-catalyzed enantioselective addition of allyltributyltin to aldehydes was also investigated by Spada and Umani-Ronchi [21], The number of noteworthy examples of asymmetric allylation of carbonyl compounds utilizing optically active catalysts of late transition metal complexes has increased since 1999. Chiral bis(oxazolinyl)phenyl rhodium(III) complex 17, developed by Mo-toyama and Nishiyama, is an air-stable and water-tolerant asymmetric Lewis acid catalyst [23,24]. Condensation of allylic stannanes with aldehydes under the influence of this catalyst results in formation of nonracemic allylated adducts with up to 80% ee (Scheme 3). In the case of the 2-butenyl addition reac-... 

In 2-p-substituted phenyl derivatives of 4-phenyl-l,3-dithiolylium ions a linear relationship exists between the 5-H resonance signals and the Hammett dithiolylium ions such as 2-amino-, 2-alkylthio- and benzo-l,3-dithiolylium ions, see (66AHC(7)39,80AHC(27)15l). 

A combination of the Pummerer rearrangement and the Ritter reaction occurs in the reaction of acetonitrile with methyl phenyl sulfoxide (equation 25) in a mixture of irifluoroacetic acid and its anhydride, although a substantial amount of the nonnal a-acetoxylation also occurs. Participation by amido groups is also possible, the interest here being largely in the construction of lactams via the intramolecular cycli-zation mode. Whereas Wolfe and his coworkers were unable to find conditions for the cyclization of S-phenylcysteinamide sulfoxides under Pummerer conditions, Kaneko found that variously substituted... 

The phenylllthlo intermediate has been isolated (20 ) and treated with styrene and ethylene oxides, and W-benzylldene aniline to provide various 2-phenyl-5-substituted pyridines. Addition of perhalomethanes affords bls(6-phenyl-3-pyrldyl)nethane and 6,6 -dlphenyl-3,3 -dlpyrldyl ( ). The yields of 3-substituted pyridines range, in the LAH reaction, from 89% for 3-plcoline to 63 for 3-benzylpyrldlne. Reaction of the LAH Intermediate with bromine formed 3-bromopyridlne in 1 1 yield (17). 

Phenylmagnesium bromide has been used to introduce a phenyl group in various substituted pyridazinones [80M1I2 811JC(B)502, 8IM112]. 

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