P-Tolyl phenyl ketone

Bourget, Bull. soc. chim. France, (3), 16, 945 (1896) Chardonnens and Schlap-bach, Helv. Chim. Acta, 29, 1413 (1946). 

To a mixture of 1 kg. of toluene and 50 g. (0.37 mole) of anhydrous aluminum chloride there is added slowly 100 g. (0.71 mole) of benzoyl chloride. (Hood.) The reaction is vigorous at first, but after it has subsided, the mixture is heated to boiling a few minutes until evolution of hydrogen chloride ceases, then cooled. An excess of water is added, and the toluene layer is separated and washed thoroughly with sodium carbonate solution. The toluene solution is dried over calcium chloride and distilled, 700 g. of toluene being recovered. The residue 

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SYNS p-BENZOPHENONE, METHYL- PHENYL p-TOLYL KETONE USAF DO-54... 

PHENYL p-TOLYL KETONE see MHF750 PHENYLTRICHLOROMETHANE see BFL250 PHENYL TRICHLOROSILANE (DOT) see TJA750 l-PHENYL-4-(3,4,5-... 

A solution of 25 g. (0.13 mole) of phenyl p-tolyl ketone (p. 260) in 130 ml. of warm acetic acid is placed under a reflux condenser. A solution of 35 g. of chromic oxide in a mixture of 80 ml. of water, 130 ml. of acetic acid, and 25 ml. of concentrated sulfuric acid is added slowly through the condenser at such a rate that the temperature of the reaction mixture remains just below the boiling point. The mixture is then refluxed for 45 minutes, and the liquid portion is poured into sufficient water to make a total volume of 2 1. The precipitated solid is filtered off and washed with water until it is white. The solid is suspended in hot water, and potassium hydroxide is added to dissolve as much solid as possible. The mixture is filtered, and the filtrate is acidified with concentrated hydrochloric acid. The precipitated acid is recrystallized from ethanol to give 18-20 g. of p-benzoylbenzoic acid which melts at 197-200° (rapid heating of bath). 

A mixture of 59 g. (0.3 mole) of phenyl p-tolyl ketone (p. 260) and 1 1. of concentrated nitric acid (sp. gr. 1.4) is held at a temperature of 80° for 10 hours. Hood.) The solid that precipitates from the cooled reaction mixture is removed by filtration and washed with nitric acid, water, and aqueous sodium carbonate solution. The solid is recrystallized from ethanol, with an activated carbon treatment, to give 47.4 g. Q5%) of 3-nitro-4-methylbenzophenone, melting at 130-131°. 

CAS 134-84-9 EINECS/ELINCS 205-159-1 Synonyms p-Benzophenone, methyl- 4-Methyl-p-benzophenone Phenyl p-tolyl ketone Empirical C H,20 Fmnula CHAMfCOCeHs... 

CAS 134-84-9 EINECS/ELINCS 205-159-1 Synonyms p-Benzophenone, methyl- 4-Methyl-p-benzophenone Phenyl p-tolyl ketone Empirical C14H12O Formula CH3C6H4COC6H5 Properties Colorless to off-wh. cryst. powd. faint odor sol. in alcohols, benzene, ether, chloroform, common org. solvs. insol. in water m.w. 196.26 ... 

Phenyl tolyl ketone. See 2-M ethyl benzophenone Phenyl p-tolyl ketone. See 4-Methylbenzophenone Phenyl-o-tolyl-methanone. See 2-Methylbenzophenone 6-Phenyl-1,3,5-triazine-2,4-diamine. See Benzoguanamine... 

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