Phenyl Boronic Acid Synthesis Clariant

Phenyl magnesium bromide and boronic acid trimethyl ester react to give phenyl-boronic acid with high selectivity (about 90%) even at room temperature, which saves energy costs and the respective CAPEX investment [177]. The yield was about 25% higher with respect to industrial batch production. Purity of the crude product could be enhanced by about 10%, thereby allowing purification by favorable crystallization only, avoiding thus the distillation steps needed in the conventional process. [Pg.248]

Finer and more uniform sized particles improve the optical properties, such as the glossiness and transparency, improving thus the commercial value of the product. [Pg.248]

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