Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Pharmacogenetics polymorphisms

Meyer UA. Genotype or phenotype the definition of a pharmacogenetic polymorphism. Pharmacogenetics 1991 1 66-67. [Pg.9]

Sellers EM, Otton SV, Tyndale RE 1997. The potential role of the cytochrome P-450 2D6 pharmacogenetic polymorphism in drug abuse. NIDA Res Monogr 173 6-26. [Pg.89]

Keywords Azathioprine methotrexate pharmacogenetics polymorphisms rhen-matoid arthritis sulfasalazine tumor necrosis factor antagonists. [Pg.413]

For the reasons stated above, pharmacogenetic polymorphisms must be defined on phenotypic grounds. Any comprehensive description of a given pharmacogenetic polymorphism should include information about the phenotype that characterizes the polymorphism and the genotype(s) that explain the polymorphism. [Pg.8]

These examples comprise only a small part of the molecular genetic studies that have been conducted on pharmacogenetic polymorphisms, They afford insights... [Pg.11]

Many Pharmacogenetic Polymorphisms are Exceptions to Experience with Single Gene Disorders... [Pg.18]

The point was made above (section 1.6) that pharmacogenetic polymorphisms usually have no perceptible effect on the health of predisposed persons, unlike other genes involved in human diseases. The frequent occurrence... [Pg.18]

Genetic disorders with abnormal reactions to environmental factors are no less treatable than many other disorders treated by physicians. These genetic disorders are treated by restricting access to, replacing and/or removing the toxic substance from the environment of the susceptible persons. Pharmacogenetic polymorphisms are invisible until their effects are revealed by exposure of individuals who harbor them to environmental toxins microarrays and allied technology provide the means to screen for these polymorphisms and to identify susceptible individuals before they are affected. [Pg.20]

U. A. Meyer, Genotype or Phenotype The Definition of a Pharmacogenetic Polymorphism , Pharmacogenetics,... [Pg.22]

Macphee I, Fredericks S, Tai T, Syrris P, Carter N, Johnston A, Goldberg L, Holt DW. Tacrolimus pharmacogenetics polymorphisms associated with expression of cytochrome P4503A5 and P-glycoprotein correlate with dose requirement. Transplantation 2002 74 1486-1489. [Pg.144]

The complex metabolism of azathioprine and mercaptopurine is subject to a pharmacogenetic polymorphism that is relevant to the degree of efficacy and toxicity... [Pg.383]

Key words Pharmacogenetics, Polymorphisms, Rheumatoid, Arthritis, Methotrexate, Azathioprine,... [Pg.625]

Key words Epigenomics, Gene, Medicine, Pediatrics, Pharmacogenetics, Polymorphism... [Pg.671]

The Potential Role of the Cytochrome P-450 2D6 Pharmacogenetic Polymorphism in Drug Abuse... [Pg.6]

Oxcarbazepine Resistance to warfarin has been described in a 16-year-old boy with the VKORCl 1173CC genot e and CYP2C9 2 allele [49 ]. It is not clear what the mechanism was in this case, nor the relevance of the pharmacogenetic polymorphisms. [Pg.711]

See other pages where Pharmacogenetics polymorphisms is mentioned: [Pg.535]    [Pg.925]    [Pg.947]    [Pg.948]    [Pg.490]    [Pg.492]    [Pg.578]    [Pg.5]    [Pg.5]    [Pg.8]    [Pg.9]    [Pg.9]    [Pg.10]    [Pg.10]    [Pg.11]    [Pg.19]    [Pg.19]    [Pg.20]    [Pg.535]    [Pg.925]    [Pg.947]    [Pg.948]    [Pg.299]    [Pg.329]    [Pg.5]    [Pg.104]    [Pg.296]    [Pg.59]    [Pg.225]    [Pg.71]    [Pg.159]    [Pg.447]   
See also in sourсe #XX -- [ Pg.2794 ]

See also in sourсe #XX -- [ Pg.63 , Pg.63 ]



SEARCH



Clinical pharmacogenetics genetic polymorphisms

Clinical pharmacogenetics polymorphism

Ethnic pharmacogenetics research polymorphisms

Pharmacogenetic

Pharmacogenetics

Pharmacogenetics of ethnic populations (cont polymorphisms

Polymorphisms pharmacogenetic loci

© 2024 chempedia.info