Phenols chlorinated, antiseptic/disinfectant

Chlorinated derivatives of phenols, cresol, and xylenol elicit the release of [ C]-glutamate from E. colt [92]. These compounds are effective bactericides and are used in crude disinfectant and antiseptic preparations such as LysoT and Det-tol . Their abUity to denature protein is probably responsible for their disruptive action upon microbial cell membranes. In addition to damaging the membrane [92], phenol exerts a lytic action upon the cell wall lysis occurs in growing cultures of E. coll [93] and is particularly noted in synchronous cultures at the point of cell division [94]. 

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