Pharmacophore maps automated generation

Although pharmacophore mapping can be completed manually in simple and straightforward cases, most of the applications require the automated generation of pharmacophore. There are several software suites available for this purpose. HipHop and Hypo-Gen are both featured by the Catalyst package. ... 

Methodologies for automated structure generation, pharmacophore mapping, and quantitative activity prediction are in the early stages of development. As more researchers report on the use of this technology, the utility and scope of the different approaches to these problems will become more evident. 

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