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Pharmacology mexiletine

Nakajima, M., Kohayashi, K., Shimada, N., Tokudome, S., Yamamoto, T. and Kuroiwa, Y. (1998) Involvement of CYP1A2 in mexiletine metabolism. British Journal of Clinical Pharmacology, 46 (1), 55-62. [Pg.232]

Mexiletine (Mexitil) is an antiarrhythmic agent with pharmacological and antiarrhythmic properties similar to those of lidocaine and tocainide. Like tocainide, mexiletine is available for oral administration. [Pg.179]

Manolis AS, Deering TF, Cameron J, Estes NA 3rd. Mexiletine pharmacology and therapeutic use. Clin Cardiol 1990 13(5) 349-59. [Pg.2332]

Although not subject to hydrolysis, mexiletine hydrochloride is metabolized by oxidative and reductive processes in the liver. Its mctabolitc.s,p-hydroxymexiletineand hydroxy-methylmcxiletine. arc nut pharmacologically active as anti-arrhythmic agents. ... [Pg.640]

Pharmacological blockade of Nayl.5 with mexiletine Churko et al. abrogates both the pathogenic increase in late Na (2013) current and APD prolongation specific to LQT3 Terrenoire... [Pg.350]

Mechanistic pharmacology approach involving propranolol, verapamil, nifedipine, diltiazem, hdocaine, mexiletine, ranolazine rescued disease phenotype... [Pg.351]

Camerino, Use-dependent block of skeletal muscle sodium current by chiral derivatives of mexiletine and tocainide and antimyotonic activity on ADR mouse, Biophys.). 72 (2) (1997) Thp72-Thp72. (d) P.E. Fenster, K.A. Comess, Pharmacology and clinical use of mexiletine. Pharmacotherapy 6 (1) (1986) 1-9. [Pg.211]


See other pages where Pharmacology mexiletine is mentioned: [Pg.605]    [Pg.178]    [Pg.191]    [Pg.312]    [Pg.191]    [Pg.258]   
See also in sourсe #XX -- [ Pg.1259 ]




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