Pharmacological and Biological Effects

SEN and Tschirren (1978). For particular pharmacologic and biologic effects of gelatin derivatives, see the following literature red cell aggregation (Thorsen and Hint 1950) and kidney function (Griem et al. 1964a,b,c Cottier et al. 1966). 

The clinical applications of HES have been reviewed by Lutz (1975) and Thompson (1978). For particular pharmacologic and biologic effects of HES see the following literature hemostasis and coagulation (Alexander 1978), intravascular persistence in humans (Thompson et al. 1970 Boon et al. 1976), and storage in animals (Lindblad and Falk 1976). 

Durbin, P. W. (1973). Metabolism and biological effects of the transplutonium elements, page 739 in Uranium, Plutonium, and the Transplutonic Elements, Handbook of Experimental Pharmacology, Vol. 36 (Springer-Verlag, Berlin). 

Description of drug substance and formulation Summaries of pharmacological and toxicological effects Summaries of pharmacokinetics and biological disposition Summary of safety and efficacy data in humans Description of possible risks and side effects. 

A pharmacological reference guide to sites of action and biological effects... 

Biochemical targets of plant bioactive compounds a pharmacological reference guide to sites of action and biological effects / Gideon Polya, p. cm. 

These authors agree that pharmacology could not evolve as a scientific discipline until modern chemistry provided the chemically pure pharmaceutical products that are needed to establish a quantitative relationship between drug dosage and biological effect. 

Polya, G. Biochemical targets of Plant Bioactive Compounds. A Pharmacological Reference Guide to Site Action and Biological Effects. CRC Press, Boca Raton, Florida, 2003, pp. 149. 

---