Pharmacogenetics databases

The reference sequences used for our pharmacogenetic studies are as follows KRAS (NM 004985 and M54968), EGFR (NM 005228.3.), CKIT (NM 000222.2), PDGFRA (NM 006206), and BRAF (NM 004333) mRNA sequences from GeneBank (http //www.ncbi.nlm.nih.gov). To compare all detected sequence variants we previously identified the most widely used mutations Internet databases listed in Table 3. 

P-Blocker and ACE inhibitor pharmacogenetic studies were identified in the PubMed database from 1966 to July 2013 by combining the following search terms heart failure, variant, polymorphism, pharmacogenetics, pharmacogenomics, p-blocker, ACE inhibitor, and each individual drug name. Studies were also identified from the reference lists of articles. Studies were limited to those performed in patients with HF and those published in English. 

Key Words Database pharmacogenetics pharmacogenomics genot5 phenotype. 

Hernandez-Boussard T, Whirl-Carrillo M, Hebert J.M, et al (2008) The pharmacogenetics and pharmacogenomics database accentuating the knowledge. Nucleic Acids Research 36 (Database issue), D913-D918... 

---