Pharmacogenetics and

Pharmacogenetics. Figure 1 Relationship between Pharmacogenetics and other disciplines illustrated using a Venn diagram. 

Pharmacogenetics and Pharmacogenomics (2000) Recent Conceptual and Technical Advances. Pharmacology 61(3) (the entire issue)... 

As pharmacogenetics and pharmacogenomics are not mutually exclusive, but even sometimes display overlapping features, both disciplines are aimed at better tailoring medical therapy for a given complex disease such as essential hypertension or other CVD. In the wake of new technologies to identify candidate region for whatever phenotype, more robust and complex bioinformatic analyses are necessary to... 

The upshot of this trend toward visibility of research should reduce liability on the part of drug manufacturers and researchers, increase the likelihood that accuracy is enhanced, and produce more informed drug users. The question of accuracy undergirds the topic of liability, and if trends toward pharmacogenetics and individualized drug therapy hold, the importance of accuracy and subsequent liability will only increase. 

DeVane, C. L. (1994). Pharmacogenetics and drug metabolism of newer antidepressant agents. /. Clin. Psychiatry, 55(38-45) 46-7. 

Meyer, U. A. (2000). Pharmacogenetics and adverse drug reactions. Lancet, 356, 1667-71. 

Murray, M. (2006). Role of CYP pharmacogenetics and drug-drug interactions in the efficacy and safety of atypical and other antipsychotic agents. /. Pharm. Pharmacol, 58, 871— 85. 

Bondy, B. Zill, P. (2004). Pharmacogenetics and psychopharmacology. Curr. Opin. Pharmacol. 4(1), 72-8. 

Kreek, M.J., Bart, G., Lilly, C., LaForge, K.S., and Nielsen, D.A., Pharmacogenetic and human molecular genetics of opiate and cocaine addictions and their treatments, Pharmacol. Rev., 57, 1, 2005. 

Pfost DR, Boyce-Jacino MT, Grant DM. A SNPshot pharmacogenetics and the future of drug therapy. Trends Bio-technol 2000 18 334-338. 

There is widespread indiscriminate use of, and thus confusion about the terms pharmacogenetics and pharmacogenomics . While no universally accepted definition exists, there is emerging consensus on the differential connotation of the two terms (see Tab. 6.1). 

Roses A. Pharmacogenetics and future dmg development and delivery. Lancet 2000 355 1358-1361. 

Nebert DW. Pharmacogenetics and phar-macogenomics why is this relevant to the clinical geneticist Clin Genet 1999 56 247-258. 

Diasio RB, Johnson MR. The role of pharmacogenetics and pharmacoge-nomics in cancer chemotherapy with 5-fluorouracil. Pharmacology 2000 61 199-203. 

Omenn GS. Prospects for Pharmacogenetics and Ecogenetics in the New Millennium. Drug Metabolism Disposition 2001 29 611-614. 

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