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Pharmaceutical industry, economic pressure

There is intense economic pressure on the pharmaceutical industry by those who pay for its products to make the development of drugs more efficient and thereby reduce or at least contain costs. Industry executives ignore this clamor at their own peril. A widely embraced strategy to improve productivity is to integrate drug discovery and development by bringing company researchers from basic, preclini-... [Pg.18]

The future of the pharmaceutical industry rests on the ability to discover and develop new molecules into products. The faster that information can be delivered to product managers and regulatory scientists, the greater the potential for shortening the time to market. Consequently, there is an economic pressure to devise instruments able to deliver many data sets at once. Coupling of instruments has become easier with expanded capabilities (HPLC-DAD-MS is almost routine, HPLC-DAD-NMR-MS is now a common commercial instrument). [Pg.356]

In conclusion, the rapid evolution of the drug regulations may invalidate this chapter within a few years, but it is important for the pharmaceutical industry to understand that the whole drug environment moves toward international standards under the pressure of the scientific progress, quality requirements and economical issues. It represents a chance to integrate Japan in the conception of the global dossier, for which ICH has already laid the foundations. [Pg.507]

In spite of the above difficulties, several companies have introduced nanoemulsions onto the market, and their benefits will be evaluated within the next few years. Nanoemulsions have been used in the pharmaceutical industry as drug-delivery systems [5], although the acceptance by customers of nanoemulsions as a new type of formulation depends on how they are perceived and their efficacy. With the advent of new instruments for high-pressure homogenisation, and the competition between various manufacturers, the cost of nanoemulsion production wiU surely and may even approach that of classic macroemulsions. Fundamental investigations into the role of surfactants in the process [6,7] will lead to optimised emulsifier systems such that a more economic use of surfactants will doubtless emerge. [Pg.273]


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