Pharmaceutical industry basic cycle

The Suzuki reaction has already found a first industrial application [24], after the catalyst Pd(TPPTS)a n HaO became available [25], In a two-phase procedure, the water-soluble catalyst effects the C-C coupling of arylboronic acis with aryl chlorides to form pharmaceutical intermediates. The Suzuki C-C cross-coupling is on the way to industrial perfection. Since the basic mechanistic features are clear by now, it is desirable that the catalysts are easy to prepare, easy to handle, and cheap, and that they bear cr-donor type ligands of which at least one does not dissociate from the metal throughout the catalytic cycle. Thus the Suzuki coupling will be seen in the syntheses of a growing number of fine chemicals and pharmaceuticals in due course. 

If items made of PHAs are composted, they are completely degraded to water and carbon dioxide as the final products of their oxidative breakdown. Here it has to be emphasized that these final oxidation products are the basic materials for the photosynthetic regeneration of carbohydrates by green plants. This demonstrates that, in contrast to petrol-based plastics, PHAs are embedded into the natural closed cycle of carbon. The range of applications for PHAs is not limited to simple packaging materials, but encompasses commodity items, materials for agro-industrial purposes and pharmaceutical and medical applications. The major advantageous characteristics of PHAs can be summarized as follows ... 

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