Phanerochaete chrysosporium, lignin degradation

An example of cometabolism of pollutants is provided by the white rot fungus Phanerochaete chrysosporium, which degrades a number of kinds of organochlorine compounds, including DDT, PCBs, and chlorodioxins, under the appropriate conditions. The enzyme system responsible for this degradation is one that the fungus uses to break down lignin in plant material under normal conditions. 

Valli K, BJ Brock, DK Joshi, MH Gold (1992a) Degradation of 2,4-dinitrotoluene by the lignin-degrading fungus Phanerochaete chrysosporium. Appl Environ Microbiol 58 221-228. 

Valli K, H Wariishi, MH Gold (1992b) Degradation of 2,7-dichlorodibenzo- -dioxin by the lignin-degrading hasidiomycete Phanerochaete chrysosporium. J Bacteriol 174 2131-2137. 

Yadav JS, CA Reddy (1993) Degradation of benzene, toluene, ethylbenzene, and xylenes (BTEX) by the lignin-degrading basidiomycete Phanerochaete chrysosporium. Appl Environ Microbiol 59 756-762. 

The degradation of chlorinated phenols has been examined with the white-rot basidiomy-cete Phanerochaete chrysosporium under conditions of nitrogen limitation, and apparently involves both lignin peroxidase and manganese-dependent peroxidase activities (Valli and Gold 1991). 

Bumpus JA, M Tatarko (1994) Biodegradation of 2,4,6-trinitrotoluene by Phanerochaete chrysosporium identification of initial degradation products and the discovery of a metabolite that inhibits lignin peroxidases. Curr Microbiol 28 185-190. 

The secretion pattern is species dependent different WRF species produce various combinations of the main lignin degrading enzymes (LiP, MnP and laccase). According to their production, WRF can be grouped in three categories [63] LiP-MnP group, like Phanerochaete chrysosporium MnP-laccase group,... 

Tien M, Kirk TK (1983) Lignin-degrading enzyme from the Hymenomycete Phanerochaete chrysosporium Burds. Science 221 661-663... 

Faison, B.D. and Kirk, T.K. (1983). Relationship between lignin degradation and production of reduced oxygen species by Phanerochaete chrysosporium. Applied arui Environmental Microbiology, 46(5), 1140-1145. 

Ligninperoxidase [9,14] Phanerochaete chrysosporium 2AH + H2O2 2A + 2H2O Degradation of lignin... 

Gold MH, Wariishi H,Valli K (1989) Extracellular peroxidases involved in lignin degradation by the white rot basidiomycete Phanerochaete chrysosporium. In Whitaker JR, Sonnet PE (eds) Biocatalysis in agricultural biotechnology. ACS symposium series 389. American Chemical Society, Washington, D.C., p 127 Thomas JA, Morris DR, Hager LP (1970) J Biol Chem 245 3135... 

Figure 1. 3-0-4 lignin substructure model compounds and products of their degradation by ligninolytic cultures of Phanerochaete chrysosporium and by lignin peroxidase. D H, and 0 of 3-ether bond and of H2 0, respectively. B and C show results of stable isotope experiments. 

Among wood-rotting fungi the basidiomycete Phanerochaete chrysosporium is able to degrade both lignin and polysaccharides from wood cell walls... 

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