Manganese dependent peroxidase

Bonnarme P, TW Jeffries (1990) Mn(ll) regulation of lignin peroxidases and manganese-dependent peroxidases from lignin-degrading white-rot fungi. Appl Environ Microbiol 56 210-217. 

The inclusion of nitrate may lead to various complications, which have been discussed in Chapter 2. In addition, the nitrogen status of the growth medium determines the levels of lignin peroxidases and manganese-dependent peroxidases that are synthesized in Phanerochaete chrysosporium. The role of Mn concentration is noted later and in Chapter 3, Part 5. 

Van der Woude MW, K Boominathan, CA Reddy (1993) Nitrogen regulation of lignin peroxidase and manganese-dependent peroxidase production is independent of carbon and manganese regulation in Phanerochaete chrysosporium. Arch Microbiol 160 1-4. 

The degradation of chlorinated phenols has been examined with the white-rot basidiomy-cete Phanerochaete chrysosporium under conditions of nitrogen limitation, and apparently involves both lignin peroxidase and manganese-dependent peroxidase activities (Valli and Gold 1991). 

Yang Q, Yang M, Pritsch K et al (2003) Decolorization of synthetic dyes and production of manganese-dependent peroxidase by new fungal isolates. Biotechnol Lett 25 709-713... 

Susla M, Svobodova K (2008) Effect of various synthetic dyes on the production of manganese-dependent peroxidase isoenzymes by immobilized Irpex lacteus. World J Microbiol Biotechnol 24 225-230... 

Watanabe, T., Katayama, S., Enoki, M., Honda, Y. Kuwahara, M. (2000). Formation of acyl radical in lipid peroxidation of linoleic acid by manganese-dependent peroxidase from Ceriporiopsis subvermispora and Bjerkandera adusta. European Journal of Biochemistry, 267, 4222-31. 

A Paszczynski, V-A Huynh, R Crawford. Enzymatic activities of an extracellular, manganese-dependent peroxidase from Phanerochaete chrysosporium. FEMS Microbiol Leff 29 37-11, 1985. 

A D Annibale, C Crestini, E De Mattia, GG Sermanni. Veratryl alcohol oxidation by manganese-dependent peroxidase from Lentinus edodes. J Biotechnol 48 231-239, 1996. 

S Lobos, J Larram, L Salas, D Cullen, R Vicuna. Isoenzymes of manganese-dependent peroxidase and laccase produced by the lignin-degrading basidiomycete Ceriporiopsis subvermispora. Microbiology-UK 140 2691-2698, 1994. 

Laccase and manganese-dependent peroxidase Polyphenol oxidase... 

Even when the fungus is grown in media with no manganese, TNT is mineralized at 50% of the rate observed with manganese containing cultures. Under these conditions there can be no manganese dependent peroxidase activity. The mechanism for mineralization under these conditions is unknown. 

In addition to catalyzing the oxidation of many compounds, LiP is also able to catalyze reductive reactions in the presence of electron donors such as EDTAor oxalate (Fig. 7) (6, 77). Veratryl alcohol is a free radical mediator in these reactions. The electron donors appear to be oxidized by a LiP generated veratryl alcohol cation radical. The resulting anion radical can catalyze the reduction of good electron acceptors such as cytochrome c, nitroblue tetrazolium, and oxygen. Evolution of CO2 from EDTA or oxalate effectively drives the reductive reactions. Similar reactions have also been observed with the manganese dependent peroxidases in the presence of quinones (20). Early work performed in our laboratory showed that these reductive mechanisms are not involved in TNT reduction. However, these reactions may be involved in other steps in TNT metabolism. 

Chung, N., M. M. Shah, T. A. Grover, and S. D. Aust. 1993. Reductive activity of a manganese-dependent peroxidase from Phanerochaete chrysosporium. Arch. Biochem. Biophys. 306 70-75. 

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