Petrosia ficiformis

Establishment of the dietary or symbiotic origin of sterols could be a difficult task, unless the tracer sterol has an unusual structure and restricted occurrence. There is little doubt, for example, that petrosterol (59) found in the nudibranch Peltodoris atromaculata [112] arises from predation of the mollusc on the sponge Petrosia ficiformis, from which the sterol was first isolated [113]. However, the origin of gorgosterol (60) in Tridacna species has not yet been established [114] despite its unusual structure. 

Castiello, D., Cimino, G., De Rosa, S., De Stefano, S., and Sondo, G., High molecular weight polyacetylenes from the nudibranch Peltodoris atromaculata and the sponge Petrosia ficiformis, Tetrahedron Lett., 21, 5047, 1980. 

Another cyclopropane sterol, petrosterol (42) was isolated as the major sterol from Petrosia ficiformis and Halichondria sp. The structure was determined as... 

Constit. of Petrosia ficiformis. Cytotoxic, inhibits sea urchin egg development, [a] +15° (CHCI3). Cimino, G. et al. Tetrahedron Lett., 1989, 30, 3563. 

Khalil, M.W., L.J. Durham, C. Djerassi, and D. Sica Ficisterol (23-Ethyl-24-methyl-27- 6)rcholesta-5,25-dien-3p-ol). A Biosynthetically Unprecedented Sterol from the Marine Sponge Petrosia ficiformis. J. Am. Chem. Soc. 102, 2133 (1980). 

Ayanoglu, E., R.D. Walkup, D. Sica, and C. Djerassi Phospholipid Studies of Marine Organisms III. New Phospholipid Fatty Acids from Petrosia ficiformis. Lipids 17, 617 (1982). 

CiMiNO, G., A. Crisping, S. de Rosa, S. de Stefano, and G. Sodano Polyacetylenes from the Sponge Petrosia ficiformis Found in Dark Caves. Experientia 37, 924 (1981). 

High Molecular Weight Polyacetylenes from the Sponge Petrosia ficiformis. J. Nat. Prod. 48, 22 (1985). 

Terretonins are meroditerpenoid mycotoxins isolated from the terrestrial species Aspergillus terreus (Springer et al., 1979 Li et al., 2005). The two new terretonins E and F were found in the marine-derived fungus Aspergillus insue-tus associated with the Mediterranean sponge Petrosia ficiformis. Both are inhibitors of the mammalian mitochondrial respiratory chain (Lopez-Gresa et al, 2009). 

Discodoris (= Peltodoris) atromacuiata, D. indecora / Petrosia ficiformis... 

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