Petasites japonica

An investigation of the metabolism of sesquiterpenoid phytoalexins has shown that pepper or potato cell cultures can convert capsidiol (485) and rishitin (450) into their 13-hydroxy-derivatives cf. p. 136). Solavetivane derivatives of this type have previously been isolated from flue-cured tobacco (Vol. 8, p. 107). New chemical and spectroscopic evidence has led to a revised configuration for the 3-hydroxy- or 3-acyloxy-substituent in furanofukinol (486) (Petasites japonica Maxim.) and the related esters (487) and (488), previously isolated from Farfugium hiberniflorum Kitam. ... 

What appear to be modified eremophilanes are bakkenolide-A (248) and related compounds from the roots of Petasites japonica (146, 314), and cacalol (249), maturinone (250), and related sesquiterpenoids from roots of Cacalia spp. (70, 221). The biogenetic relationship of these compounds to eremophilanes is strengthened by the co-occurrence of decompostin (251) (339) with cacalol and related compounds in C decomposita (221). 

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