Pesticide poisoning anticonvulsants

Diazepam is the anticonvulsant that has been most studied for use in OP pesticide poisoning. In this context, the most likely mode of administration i.s by intravenous injection, but other modes of administration have been considered for self-administration or when administration by those not trained in inlravcnou.s injection is required. In OP-induced convulsions, diazepam would be given intravenously. 

Solanine hydrochloride has been used as a commercial pesticide. It has sedative and anticonvulsant properties, and has sometimes been used for the treatment of asthma, as well as for cough and common cold. However, gastrointestinal and neurological disorders result from solanine poisoning. Symptoms include nausea, diarrhoea, vomiting, stomach cramps, burning of the throat, headaches and dizziness. Other adverse reactions, in more severe cases, include hallucinations, loss of sensation, paralysis, fever, jaundice, dilated pupils and hypothermia. Solanine overdose can be fatal. 

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